User profiles for "author:S Linn"

Shai Linn

- Verified email at univ.haifa.ac.il - Cited by 71686

Sabine Linn

- Verified email at nki.nl - Cited by 18592

[HTML][HTML] Meditation programs for psychological stress and well-being: a systematic review and meta-analysis

…, HM Shihab, PD Ranasinghe, S Linn… - JAMA internal …, 2014 - jamanetwork.com
Importance Many people meditate to reduce psychological stress and stress-related health
problems. To counsel people appropriately, clinicians need to know what the evidence says …

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

…, K Ünsal-Kaçmaz, S Linn - Annual review of …, 2004 - annualreviews.org
▪ Abstract DNA damage is a relatively common event in the life of a cell and may lead to
mutation, cancer, and cellular or organismic death. Damage to DNA induces several cellular …

DNA damage and oxygen radical toxicity

JA Imlay, S Linn - Science, 1988 - science.org
A major portion of the toxicity of hydrogen peroxide in Escherichia coli is attributed to DNA
damage mediated by a Fenton reaction that generates active forms of hydroxyl radicals from …

Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 32 cancer groups, 1990 to …

…, YS Khader, YH Khang, D Kim, J Leigh, S Linn… - JAMA …, 2017 - jamanetwork.com
Importance Cancer is the second leading cause of death worldwide. Current estimates on
the burden of cancer are needed for cancer control planning. Objective To estimate …

Global, regional, and national burden of cardiovascular diseases for 10 causes, 1990 to 2015

…, GA Kumar, GF Kwan, DK Lal, A Larsson, S Linn… - Journal of the American …, 2017 - jacc.org
Background: The burden of cardiovascular diseases (CVDs) remains unclear in many
regions of the world. Objectives: The GBD (Global Burden of Disease) 2015 study integrated …

[HTML][HTML] Smoking prevalence and attributable disease burden in 195 countries and territories, 1990–2015: a systematic analysis from the Global Burden of Disease …

…, GA Kumar, JL Leasher, A Lee, M Leinsalu, T Li, S Linn… - The Lancet, 2017 - thelancet.com
Background The scale-up of tobacco control, especially after the adoption of the Framework
Convention for Tobacco Control, is a major public health success story. Nonetheless …

Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 29 cancer groups, 1990 to …

…, A Lafranconi, Q Lan, Y Legesse, J Leigh, S Linn… - JAMA …, 2018 - jamanetwork.com
Importance The increasing burden due to cancer and other noncommunicable diseases
poses a threat to human development, which has resulted in global political commitments …

Toxic DNA damage by hydrogen peroxide through the Fenton reaction in vivo and in vitro

JA Imlay, SM Chin, S Linn - Science, 1988 - science.org
Exposure of Escherichia coli to low concentrations of hydrogen peroxide results in DNA
damage that causes mutagenesis and kills the bacteria, whereas higher concentrations of …

[PDF][PDF] A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer

K Berns, HM Horlings, BT Hennessy, M Madiredjo… - Cancer cell, 2007 - cell.com
A large-scale RNA interference screen to discover genes involved in trastuzumab resistance
in breast cancer identified only PTEN as a modulator of drug sensitivity. Oncogenic mutants …

[HTML][HTML] Formation, prevention, and repair of DNA damage by iron/hydrogen peroxide

ES Henle, S Linn - Journal of Biological Chemistry, 1997 - ASBMB
Although oxygen is a powerful oxidant, the triplet ground state of dioxygen constitutes a
kinetic barrier for oxidation of biological molecules, which are mostly singlet state (1) …