The use of immunomodulation to treat malignancies has seen a recent explosion in interest.
The therapeutic appeal of these treatments is far reaching, and many new applications …

Background Roots are essential organs for higher plants. They provide the plant with
nutrients and water, anchor the plant in the soil, and can serve as energy storage organs …

By following the evolution of populations that are initially genetically homogeneous, much
can be learned about core biological principles. For example, it allows for detailed studies of …

Large-scale phenotyping of multicellular organisms is one of the current challenges in
biology. We present a comprehensive and scalable pipeline that allows for the efficient …

Root system architecture (RSA), the distribution of roots in soil, plays a major role in plant
survival. RSA is shaped by multiple developmental processes that are largely governed by …

Low availability of Fe significantly limits crop yields in many parts of the world. However, it is
largely unknown which genes and alleles adjust plant growth in Fe limited environments …

Extracellular vesicles (EVs) are efficient natural vehicles for intercellular communication and
are under extensive investigation for the delivery of diverse therapeutics including small …

Two elderly women with complex medical histories presented with erythematous patches, in
one case involving the face and forearms, and in the other both elbows. Punch biopsies from …

Regulation of plant root angle is critical for obtaining nutrients and water and is an important
trait for plant breeding. A plant's final, long-term root angle is the net result of a complex …

From the cellular perspective, organ growth is determined by production and growth of cells.
Uncovering how these two processes are coordinated is essential for understanding …