User profiles for "author:R Perkins"

Roger Perkins

- Verified email at fda.hhs.gov - Cited by 15284

Rosie Perkins

- Verified email at wlab.gu.se - Cited by 4844

Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis

CS Fox, K Matsushita, M Woodward, HJG Bilo… - The Lancet, 2012 - thelancet.com
Background Chronic kidney disease is characterised by low estimated glomerular filtration
rate (eGFR) and high albuminuria, and is associated with adverse outcomes. Whether these …

The toxicology of perfluorooctanoate

GL Kennedy, JL Butenhoff, GW Olsen… - Critical reviews in …, 2004 - Taylor & Francis
ABSTRACT PFOA is a peroxisome proliferator (PPAR agonist) and exerts morphological
and biochemical effects characteristic of PPAR agonists. These effects include increased β …

A meta-analysis of the association of estimated GFR, albuminuria, diabetes mellitus, and hypertension with acute kidney injury

…, J Green, H Les Kirchner, R Perkins… - American Journal of …, 2015 - Elsevier
Background Diabetes mellitus and hypertension are risk factors for acute kidney injury (AKI).
Whether estimated glomerular filtration rate (eGFR) and urine albumin-creatinine ratio …

The MicroArray Quality Control (MAQC) project shows inter-and intraplatform reproducibility of gene expression measurements.

L Shi, LH Reid, WD Jones, R Shippy… - Nature …, 2006 - europepmc.org
Over the last decade, the introduction of microarray technology has had a profound impact
on gene expression research. The publication of studies with dissimilar or altogether …

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

…, D Torrents, R Burcelin, W Ricart, R Perkins… - Nature medicine, 2017 - nature.com
Metformin is widely used in the treatment of type 2 diabetes (T2D), but its mechanism of
action is poorly defined. Recent evidence implicates the gut microbiota as a site of metformin …

The estrogen receptor relative binding affinities of 188 natural and xenochemicals: structural diversity of ligands

…, CL Moland, W Tong, L Shi, R Perkins… - Toxicological …, 2000 - academic.oup.com
We have utilized a validated (standardized) estrogen receptor (ER) competitive-binding
assay to determine the ER affinity for a large, structurally diverse group of chemicals. Uteri …

Uses and abuses of recovery: implementing recovery‐oriented practices in mental health systems

…, B Hamilton, M O'Hagan, G Panther, R Perkins… - World …, 2014 - Wiley Online Library
An understanding of recovery as a personal and subjective experience has emerged within
mental health systems. This meaning of recovery now underpins mental health policy in …

[HTML][HTML] 2019 ASCCP risk-based management consensus guidelines for abnormal cervical cancer screening tests and cancer precursors

RB Perkins, RS Guido, PE Castle… - Journal of lower …, 2020 - journals.lww.com
Rebecca B. Perkins, MD, MSc, 1 Richard S. Guido, MD, 2 Philip E. Castle, PhD, 3 David
Chelmow, MD, 4 Mark H. Einstein, MD, MS, 5 Francisco Garcia, MD, MPH, 6 Warner K. Huh …

Current status of methods for defining the applicability domain of (quantitative) structure-activity relationships: The report and recommendations of ecvam workshop 52

…, GY Patlewicz, R Perkins… - Alternatives to …, 2005 - journals.sagepub.com
This is the 52nd report of a series of workshops organised by the European Centre for the
Validation of Alternative Methods (ECVAM). The main objective of ECVAM, as defined in …

[HTML][HTML] The gut microbiota modulates host energy and lipid metabolism in mice [S]

…, L Yetukuri, S Islam, J Felin, R Perkins… - Journal of lipid …, 2010 - ASBMB
The gut microbiota has recently been identified as an environmental factor that may promote
metabolic diseases. To investigate the effect of gut microbiota on host energy and lipid …