User profiles for "author:Michael R Elliott"

Michael R Elliott

- Verified email at umich.edu - Cited by 9105

Michael R. Elliott

- Verified email at southalabama.edu - Cited by 7327

Clearance of apoptotic cells: implications in health and disease

MR Elliott, KS Ravichandran - Journal of Cell Biology, 2010 - rupress.org
Recent advances in defining the molecular signaling pathways that regulate the
phagocytosis of apoptotic cells have improved our understanding of this complex and …

Efferocytosis signaling in the regulation of macrophage inflammatory responses

MR Elliott, KM Koster, PS Murphy - The Journal of Immunology, 2017 - journals.aai.org
Since the pioneering work of Elie Metchnikoff and the discovery of cellular immunity, the
phagocytic clearance of cellular debris has been considered an integral component of …

[PDF][PDF] The dynamics of apoptotic cell clearance

MR Elliott, KS Ravichandran - Developmental cell, 2016 - cell.com
The phagocytic clearance of dying cells in a tissue is a highly orchestrated series of
intercellular events coordinated by a complex signaling network. Recent data from genetic …

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

MR Elliott, FB Chekeni, PC Trampont, ER Lazarowski… - Nature, 2009 - nature.com
Phagocytic removal of apoptotic cells occurs efficiently in vivo such that even in tissues with
significant apoptosis, very few apoptotic cells are detectable. This is thought to be due to the …

“Sparse” temporal sampling in auditory fMRI

DA Hall, MP Haggard, MA Akeroyd… - Human brain …, 1999 - Wiley Online Library
The use of functional magnetic resonance imaging (fMRI) to explore central auditory function
may be compromised by the intense bursts of stray acoustic noise produced by the scanner …

Pannexin 1 channels mediate 'find-me'signal release and membrane permeability during apoptosis

FB Chekeni, MR Elliott, JK Sandilos, SF Walk… - Nature, 2010 - nature.com
Apoptotic cells release 'find-me'signals at the earliest stages of death to recruit phagocytes.
The nucleotides ATP and UTP represent one class of find-me signals, but their mechanism …

BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module

D Park, AC Tosello-Trampont, MR Elliott, M Lu… - Nature, 2007 - nature.com
Engulfment and subsequent degradation of apoptotic cells is an essential step that occurs
throughout life in all multicellular organisms,,. ELMO/Dock180/Rac proteins are a conserved …

Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2

A Kadl, AK Meher, PR Sharma, MY Lee… - Circulation …, 2010 - Am Heart Assoc
Rationale: Macrophages change their phenotype and biological functions depending on the
microenvironment. In atherosclerosis, oxidative tissue damage accompanies chronic …

Belt-positioning booster seats and reduction in risk of injury among children in vehicle crashes

DR Durbin, MR Elliott, FK Winston - Jama, 2003 - jamanetwork.com
ContextAlthough more than a dozen states have ratified laws that require booster seats for
children older than 4 years, most states continue to have child restraint laws that only cover …

Effectiveness of child safety seats vs seat belts in reducing risk for death in children in passenger vehicle crashes

MR Elliott, MJ Kallan, DR Durbin… - Archives of pediatrics & …, 2006 - jamanetwork.com
Objective To provide an estimate of benefit, if any, of child restraint systems over seat belts
alone for children aged from 2 through 6 years. Design Cohort study. Setting A sample of …