User profiles for "author:Ilkka Ojanperä"

Ilkka Ojanperä

Professor of Forensic Toxicology
Verified email at helsinki.fi
Cited by 7865

Current use of high-resolution mass spectrometry in drug screening relevant to clinical and forensic toxicology and doping control

I Ojanperä, M Kolmonen, A Pelander - Analytical and bioanalytical …, 2012 - Springer
Clinical and forensic toxicology and doping control deal with hundreds or thousands of
drugs that may cause poisoning or are abused, are illicit, or are prohibited in sports. Rapid …

Isotopic pattern and accurate mass determination in urine drug screening by liquid chromatography/time‐of‐flight mass spectrometry

S Ojanperä, A Pelander, M Pelzing… - … Journal Devoted to …, 2006 - Wiley Online Library
An efficient method was developed for toxicological drug screening in urine by liquid
chromatography coupled with electrospray ionization time‐of‐flight mass spectrometry. The …

Simultaneous screening for 238 drugs in blood by liquid chromatography–ionspray tandem mass spectrometry with multiple-reaction monitoring

M Gergov, I Ojanperä, E Vuori - Journal of Chromatography B, 2003 - Elsevier
A liquid chromatography–tandem mass spectrometry (LC–MS–MS) method is presented for
the qualitative screening for 238 drugs in blood samples, which is considerably more than in …

A general screening method for doping agents in human urine by solid phase extraction and liquid chromatography/time-of-flight mass spectrometry

M Kolmonen, A Leinonen, A Pelander, I Ojanperä - Analytica Chimica Acta, 2007 - Elsevier
A general screening method based on solid phase extraction (SPE) and liquid
chromatography/time-of-flight mass spectrometry (LC/TOFMS) was developed and …

Profiles of pregabalin and gabapentin abuse by postmortem toxicology

M Häkkinen, E Vuori, E Kalso, M Gergov… - Forensic science …, 2014 - Elsevier
Pregabalin (PRG) and gabapentin (GBP) are used in the treatment of neuropathic pain and
epilepsy, and PRG also in generalized anxiety disorder. There is increasing evidence that …

Simultaneous screening and quantification of 25 opioid drugs in post-mortem blood and urine by liquid chromatography–tandem mass spectrometry

M Gergov, P Nokua, E Vuori, I Ojanperä - Forensic science international, 2009 - Elsevier
A method for simultaneous screening and quantification was developed for the fentanyls
alfentanil, fentanyl, p-fluorofentanyl, cis-3-methylfentanyl, trans-3-methylfentanyl, alpha …

A high-sensitivity ultra-high performance liquid chromatography/high-resolution time-of-flight mass spectrometry (UHPLC-HR-TOFMS) method for screening synthetic …

M Sundström, A Pelander, V Angerer, M Hutter… - Analytical and …, 2013 - Springer
The continuing emergence of designer drugs imposes high demands on the scope and
sensitivity of toxicological drug screening procedures. An ultra-high performance liquid …

Benzodiazepines and alcohol are associated with cases of fatal buprenorphine poisoning

M Häkkinen, T Launiainen, E Vuori… - European journal of clinical …, 2012 - Springer
Background Although buprenorphine therapy has proved to be successful in opioid
maintenance treatments, the drug is also widely abused in many countries by intravenous …

Toxicological screening with formula-based metabolite identification by liquid chromatography/time-of-flight mass spectrometry

A Pelander, I Ojanperä, S Laks, I Rasanen… - Analytical …, 2003 - ACS Publications
An analytical procedure was evaluated for the comprehensive toxicological screening of
drugs, metabolites, and pesticides in 1-mL urine samples by TurboIon spray liquid …

Post-mortem SNP analysis of CYP2D6 gene reveals correlation between genotype and opioid drug (tramadol) metabolite ratios in blood

A Levo, A Koski, I Ojanperä, E Vuori… - Forensic science …, 2003 - Elsevier
Tramadol is an opioid drug metabolised in phase I by cytochrome P450 (CYP) enzymes, of
which CYP2D6 is mainly responsible for the O-demethylation of tramadol, but is not involved …