Barbiturates for acute traumatic brain injury

I Roberts, E Sydenham - Cochrane Database of Systematic …, 2012 - cochranelibrary.com
Background Raised intracranial pressure (ICP) is an important complication of severe brain
injury, and is associated with high mortality. Barbiturates are believed to reduce ICP by …

Omega 3 fatty acid for the prevention of cognitive decline and dementia

E Sydenham, AD Dangour… - Cochrane Database of …, 2012 - cochranelibrary.com
Background Evidence from observational studies suggests that diets high in omega‐3 long‐
chain polyunsaturated fatty acids (PUFA) may protect people from cognitive decline and …

Hypothermia for traumatic head injury

E Sydenham, I Roberts… - Cochrane Database of …, 2009 - cochranelibrary.com
Background Hypothermia has been used in the treatment of head injury for many years.
Encouraging results from small trials and laboratory studies led to renewed interest in the …

[HTML][HTML] Anti-fibrinolytic agents in post partum haemorrhage: a systematic review

P Ferrer, I Roberts, E Sydenham, K Blackhall… - BMC pregnancy and …, 2009 - Springer
Background Post partum haemorrhage is a leading cause of maternal death worldwide. It
also contributes to maternal morbidity as women may require a hysterectomy to control …

Glucocorticoid with cyclophosphamide for paraquat‐induced lung fibrosis

LR Li, E Sydenham, B Chaudhary… - Cochrane database of …, 2010 - cochranelibrary.com
Background Paraquat is an effective and widely used herbicide but is also a lethal poison. In
many developing countries paraquat is widely available and inexpensive, making poisoning …

The knowledge system underpinning healthcare is not fit for purpose and must change

I Roberts, K Ker, P Edwards, D Beecher, D Manno… - Bmj, 2015 - bmj.com
The knowledge system underpinning healthcare is not fit for purpose and must change Page 1
The knowledge system underpinning healthcare is not fit for purpose and must change The …

Omega 3 fatty acids and cognitive health in older people

AD Dangour, VA Andreeva, E Sydenham… - British Journal of …, 2012 - cambridge.org
Oily fish and other sources of long-chain n-3 polyunsaturated fatty acids (n-3 LCPs) have
been proposed as protective against dementia and age related cognitive impairment. The …

Identifying and managing problematic trials: A research integrity assessment tool for randomized controlled trials in evidence synthesis

S Weibel, M Popp, S Reis, N Skoetz… - Research Synthesis …, 2023 - Wiley Online Library
Evidence synthesis findings depend on the assumption that the included studies follow good
clinical practice and results are not fabricated or false. Studies which are problematic due to …

Protocol for the development of a tool (INSPECT-SR) to identify problematic randomised controlled trials in systematic reviews of health interventions

J Wilkinson, C Heal, GA Antoniou, E Flemyng… - BMJ open, 2024 - bmjopen.bmj.com
Introduction Randomised controlled trials (RCTs) inform healthcare decisions. It is now
apparent that some published RCTs contain false data and some appear to have been …

[HTML][HTML] Protocol: Protocol for the development of a tool (INSPECT-SR) to identify problematic randomised controlled trials in systematic reviews of health interventions

J Wilkinson, C Heal, GA Antoniou, E Flemyng… - BMJ Open, 2024 - ncbi.nlm.nih.gov
ABSTRACT Introduction Randomised controlled trials (RCTs) inform healthcare decisions. It
is now apparent that some published RCTs contain false data and some appear to have …