Vitamin D and DBP: the free hormone hypothesis revisited

RF Chun, BE Peercy, ES Orwoll, CM Nielson… - The Journal of steroid …, 2014 - Elsevier
The last five years have witnessed a remarkable renaissance in vitamin D research and a
complete re-evaluation of its benefits to human health. Two key factors have catalyzed these …

Osteoporosis in men

ES Orwoll, RF Klein - Endocrine reviews, 1995 - academic.oup.com
I. Introduction A LTHOUGH osteoporosis has long been considered a disease of women, in
the earliest reports of the epidemiology of osteoporosis it was apparent that the classical age …

Skeletal health in long‐duration astronauts: nature, assessment, and management recommendations from the NASA bone summit

ES Orwoll, RA Adler, S Amin, N Binkley… - Journal of bone and …, 2013 - academic.oup.com
Concern about the risk of bone loss in astronauts as a result of prolonged exposure to
microgravity prompted the National Aeronautics and Space Administration to convene a …

Prevalence of low femoral bone density in older US adults from NHANES III

AC Looker, ES Orwoll, CC Johnston JR… - Journal of Bone and …, 1997 - academic.oup.com
Most estimates of osteoporosis in older US adults have been based on its occurrence in
white women, even though it is known to affect men and minority women. In the present …

A comparison of frailty indexes for the prediction of falls, disability, fractures, and mortality in older men

KE Ensrud, SK Ewing, PM Cawthon… - Journal of the …, 2009 - Wiley Online Library
OBJECTIVES: To compare the validity of a parsimonious frailty index (components: weight
loss, inability to rise from a chair, and poor energy (Study of Osteoporotic Fractures (SOF) …

The effect of teriparatide [human parathyroid hormone (1–34)] therapy on bone density in men with osteoporosis

ES Orwoll, WH Scheele, S Paul, S Adami… - Journal of bone and …, 2003 - academic.oup.com
Abstract Teriparatide [rhPTH (1–34)] increases bone mineral density and reduces the risk of
vertebral fracture in women. We randomized 437 men with spine or hip bone mineral density …

Hip fracture in women without osteoporosis

SA Wainwright, LM Marshall, KE Ensrud… - The Journal of …, 2005 - academic.oup.com
The proportion of fractures that occur in women without osteoporosis has not been fully
described, and the characteristics of nonosteoporotic women who fracture are not well …

[HTML][HTML] The clinical diagnosis of osteoporosis: a position statement from the National Bone Health Alliance Working Group

ES Siris, R Adler, J Bilezikian, M Bolognese… - Osteoporosis …, 2014 - Springer
Osteoporosis causes an elevated fracture risk. We propose the continued use of T-scores as
one means for diagnosis but recommend that, alternatively, hip fracture; osteopenia …

Testosterone influences spatial cognition in older men.

JS Janowsky, SK Oviatt, ES Orwoll - Behavioral neuroscience, 1994 - psycnet.apa.org
Testosterone (TST) plays a role in the organization of behavior during development. The
authors examined whether TST could play a maintenance role in behavior as well. In a …

Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture

HF Zheng, V Forgetta, YH Hsu, K Estrada… - Nature, 2015 - nature.com
The extent to which low‐frequency (minor allele frequency (MAF) between 1–5%) and rare
(MAF≤ 1%) variants contribute to complex traits and disease in the general population is …