Given the sensitive topic of drug abuse and the private nature of the family, researchers must overcome a number of methodological obstacles when studying drug abuse and the family. The purpose of this study was to determine whether adolescents would provide honest and accurate answers to drug use questions in the context of their homes with their families participating in the same survey. Although there is no direct objective validation of the self-report measures used in this study, evidence from the analysis of the survey data suggests that adolescent self-reports are, in most cases, reliable and valid, and that the setting in which respondents complete questionnaires does not, in general, result in systematic reporting bias.