Description of additional permanent concussion substitutes (APCSs) used in the 2020–2021 Premier League season
| Event no. | No. players involved | Position of injured player | Action of player before injury | Mechanism of injury | Time of medical assessment (s) | No. signs of concussion | Return to play following assessment |
| 1 | 2 | Defender | Sliding/tackling | Knee-to-head | 186 | 3 | Immediately removed from play |
| 2 | 2 | Goalkeeper | Sliding/tackling | Knee-to-head | 900 | 4 | Immediately removed from play |
| 3 | 2 | Defender | Sliding/tackling | Head-to-field | 180 | 3 | Returned to play before removal |