Exposure period in days prior to the index date, adjusted OR (95% CI)* | |||||
---|---|---|---|---|---|
Drivers’ age | Number of different medications | 1–8 | 1–15 | 1–30 | 1–90 |
50–65 years | 0 | 1 | 1 | 1 | 1 |
1–2 | 1.10 (1.03 to 1.18) | 1.11 (1.05 to 1.18) | 1.11 (1.06 to 1.16) | 1.09 (1.04 to 1.13) | |
3–4 | 1.24 (1.09 to 1.42) | 1.19 (1.08 to 1.32) | 1.14 (1.05 to 1.23) | 1.12 (1.06 to 1.19) | |
≥5 | 1.43 (1.18 to 1.73) | 1.57 (1.37 to 1.80) | 1.47 (1.34 to 1.62) | 1.38 (1.30 to 1.48) | |
66–80 years | 0 | 1 | 1 | 1 | 1 |
1–2 | 1.27 (1.16 to 1.39) | 1.17 (1.08 to 1.25) | 1.15 (1.08 to 1.23) | 1.04 (0.97 to 1.12) | |
3–4 | 1.33 (1.13 to 1.57) | 1.23 (1.09 to 1.40) | 1.21 (1.09 to 1.33) | 1.17 (1.07 to 1.28) | |
≥5 | 1.32 (1.06 to 1.64) | 1.25 (1.06 to 1.46) | 1.39 (1.24 to 1.57) | 1.28 (1.16 to 1.41) |
*From conditional logistic regression for cases and controls matched by sex, age and place of residence, and adjusted for civil status, occupation and cardiovascular and nervous system medications.
ATC, anatomical therapeutic chemical classification.