Table 1

Examples of cluster randomised trials of injury interventions

StudyUnit of randomisationInterventionPrimary outcome(s)Number of clustersAverage cluster sizeEstimated ICC
Bennewith et al 20023General practices in specified hospital catchment areasMailing for GPs about index episode of self-harm in registered patient, guidelines for managementRepeat episodes of self-harm98 general practices20 patients per practice0.006 for repeat episode of deliberate self-harm
Blake et al 20084SchoolsBicycle helmet curriculum and demonstration, individual fit check and feedback within classCorrect helmet use12 schools14 children per schoolNot provided
Cox et al 20085Primary care organisations (PCOs)Training on fracture prevention; feedback from specialist nurses to staff and GP on each patient's fall risk, with recommendationsAll fractures and hip fractures58 primary care organisationsFour care homes per PCO0.20 for all fractures
0.21 for hip fracture
Cumming et al 20086Hospital wardsTargeted multi-factorial intervention (patient risk assessment, education, exercise, bed alarms, and drug review; modification of bedside and ward environment; staff training)Falls24 hospital wards167 patients per ward0.014 unadjusted
0.003 adjusted for length of stay and previous falls
DiGuiseppi et al 20027Electoral wardsDoor-to-door distribution of smoke alarmsFire-related injuries40 electoral wards3686 households per ward0.00017 for all preventable injuries, 0.00011 for preventable hospitalisations and death
Kendrick et al 19998General practicesSafety advice at three child health surveillance consultations; low cost safety equipment to families on means tested state benefits; home safety checks and first aid training by health visitorsMedically attended injuries36 general practices55 children per general practice0.017 for medically attended injury
Kendrick et al 20059General practicesTraining for midwives and health visitors; educational package delivered by midwives and health visitors to parents to reduce baby walker possession and useSelf-reported possession and use of baby walker64 general practices16 mothers per practice0.053 for possession of baby walker 0.050 for use of baby walker
Kendrick et al 200710Schools‘Risk Watch’ programme delivered by teachers as classroom curriculum (safety); teachers trained and provided with materialsSafety knowledge20 schools23 schoolchildren per schoolKnowledge scores:
ICC for fire and burn prevention 0.187,
poisoning prevention 0.097, bike and pedestrian safety 0.072, falls prevention 0.234
Mulvaney et al 200611SchoolsReflective visibility aids, educational booklet, parent letter; usual road safety educationWearing of visibility aids20 school classes (one per school)19 children per class0.45 for any visibility aid at 1 week after intervention, 0.21 at 8 weeks
Olsen et al 200512Handball sports clubsA structured warm-up programme to improve running, cutting, and landing technique as well as neuromuscular control, balance, and strengthAcute injury to the knee or ankle120 clubs15 players per club0.057 for acute injury to the knee or ankle, 0.043 for all injuries
  • GP, general practitioner; ICC, intraclass correlation coefficient.