RT Journal Article SR Electronic T1 Evaluation of the efficacy of an intersection conflict warning system at two-way stop-controlled rural intersections: difference-in-differences and triple-difference analytical approaches JF Injury Prevention JO Inj Prev FD BMJ Publishing Group Ltd SP injuryprev-2021-044321 DO 10.1136/injuryprev-2021-044321 A1 Disi Tian A1 Susan G Gerberich A1 Hyun Kim A1 Andrew D Ryan A1 Darin J Erickson A1 Nichole L Morris YR 2021 UL http://injuryprevention.bmj.com/content/early/2021/10/28/injuryprev-2021-044321.abstract AB Objective Intersection conflict warning systems (ICWSs) have been implemented at high-risk two-way stop-controlled intersections to prevent right-angle crashes and associated injuries. This study involved investigation of the impacts of ICWSs on crash reductions.Methods The study used a quasi-experimental design to analyse the potential causal relations between Minnesota’s ICWSs and various crash rate outcomes (including total, injury, non-injury, targeted right-angle and non-right-angle crashes) in pre-post analyses. A restricted randomisation method enabled identification of three controls to each ICWS treatment intersection, and included as many comparable intersection characteristics as possible. Annual crash rates (per year per intersection) were analysed over the same periods before and after system activation for treatment and control intersections in each matched group. Pre-crash data for 3 years and post-crash data for up to 5 years were included, ranging from 2010 to 2018. Negative binomial regression models with generalised estimating equations were applied to estimate the average, immediate and continuing treatment effects of ICWSs, through the difference-in-differences and difference-in-difference-in-difference approaches, respectively.Results The ICWS treatment was significantly associated with a decreasing trend for targeted right-angle crash rates posttreatment. Although not statistically significant, most crash rate outcomes appeared to be elevated immediately after treatment (statistically significant for sideswipe crashes only). Pre–post differences in average crash rates (over entire periods), except for incapacitating injury-related crashes, were not statistically significant between treatment and control intersections.Conclusions The study provided important insight into potential causal associations between intersection safety countermeasures and crashes at high-risk rural two-way stop-controlled intersections.Data are available upon reasonable request. Data may be obtained from a third party and are not publicly available.