RT Journal Article SR Electronic T1 Morbidity and mortality from road injuries: results from the Global Burden of Disease Study 2017 JF Injury Prevention JO Inj Prev FD BMJ Publishing Group Ltd SP i46 OP i56 DO 10.1136/injuryprev-2019-043302 VO 26 IS Suppl 2 A1 Spencer L James A1 Lydia R Lucchesi A1 Catherine Bisignano A1 Chris D Castle A1 Zachary V Dingels A1 Jack T Fox A1 Erin B Hamilton A1 Zichen Liu A1 Darrah McCracken A1 Molly R Nixon A1 Dillon O Sylte A1 Nicholas L S Roberts A1 Oladimeji M Adebayo A1 Teamur Aghamolaei A1 Suliman A Alghnam A1 Syed Mohamed Aljunid A1 Amir Almasi-Hashiani A1 Alaa Badawi A1 Masoud Behzadifar A1 Meysam Behzadifar A1 Eyasu Tamru Bekru A1 Derrick A Bennett A1 Jens Robert Chapman A1 Kebede Deribe A1 Bereket Duko Adema A1 Yousef Fatahi A1 Belayneh K Gelaw A1 Eskezyiaw Agedew Getahun A1 Delia Hendrie A1 Andualem Henok A1 Hagos de Hidru A1 Mehdi Hosseinzadeh A1 Guoqing Hu A1 Mohammad Ali Jahani A1 Mihajlo Jakovljevic A1 Farzad Jalilian A1 Nitin Joseph A1 Manoochehr Karami A1 Abraham Getachew Kelbore A1 Md Nuruzzaman Khan A1 Yun Jin Kim A1 Parvaiz A Koul A1 Carlo La Vecchia A1 Shai Linn A1 Reza Majdzadeh A1 Man Mohan Mehndiratta A1 Peter T N Memiah A1 Melkamu Merid Mengesha A1 Hayimro Edemealem Merie A1 Ted R Miller A1 Mehdi Mirzaei-Alavijeh A1 Aso Mohammad Darwesh A1 Naser Mohammad Gholi Mezerji A1 Roghayeh Mohammadibakhsh A1 Yoshan Moodley A1 Maziar Moradi-Lakeh A1 Kamarul Imran Musa A1 Bruno Ramos Nascimento A1 Rajan Nikbakhsh A1 Peter S Nyasulu A1 Ahmed Omar Bali A1 Obinna E Onwujekwe A1 Sanghamitra Pati A1 Reza Pourmirza Kalhori A1 Farkhonde Salehi A1 Saeed Shahabi A1 Seifadin Ahmed Shallo A1 Morteza Shamsizadeh A1 Zeinab Sharafi A1 Sharvari Rahul Shukla A1 Mohammad Reza Sobhiyeh A1 Joan B Soriano A1 Bryan L Sykes A1 Rafael Tabarés-Seisdedos A1 Degena Bahray Bahrey Tadesse A1 Yonatal Mesfin Tefera A1 Arash Tehrani-Banihashemi A1 Boikhutso Tlou A1 Roman Topor-Madry A1 Taweewat Wiangkham A1 Mehdi Yaseri A1 Sanni Yaya A1 Muluken Azage Yenesew A1 Mustafa Z Younis A1 Arash Ziapour A1 Sanjay Zodpey A1 David M Pigott A1 Robert C Reiner, Jr A1 Simon I Hay A1 Alan D Lopez A1 Ali H Mokdad YR 2020 UL http://injuryprevention.bmj.com/content/26/Suppl_2/i46.abstract AB Background The global burden of road injuries is known to follow complex geographical, temporal and demographic patterns. While health loss from road injuries is a major topic of global importance, there has been no recent comprehensive assessment that includes estimates for every age group, sex and country over recent years.Methods We used results from the Global Burden of Disease (GBD) 2017 study to report incidence, prevalence, years lived with disability, deaths, years of life lost and disability-adjusted life years for all locations in the GBD 2017 hierarchy from 1990 to 2017 for road injuries. Second, we measured mortality-to-incidence ratios by location. Third, we assessed the distribution of the natures of injury (eg, traumatic brain injury) that result from each road injury.Results Globally, 1 243 068 (95% uncertainty interval 1 191 889 to 1 276 940) people died from road injuries in 2017 out of 54 192 330 (47 381 583 to 61 645 891) new cases of road injuries. Age-standardised incidence rates of road injuries increased between 1990 and 2017, while mortality rates decreased. Regionally, age-standardised mortality rates decreased in all but two regions, South Asia and Southern Latin America, where rates did not change significantly. Nine of 21 GBD regions experienced significant increases in age-standardised incidence rates, while 10 experienced significant decreases and two experienced no significant change.Conclusions While road injury mortality has improved in recent decades, there are worsening rates of incidence and significant geographical heterogeneity. These findings indicate that more research is needed to better understand how road injuries can be prevented.