PT - JOURNAL ARTICLE AU - Spencer L James AU - Lydia R Lucchesi AU - Catherine Bisignano AU - Chris D Castle AU - Zachary V Dingels AU - Jack T Fox AU - Erin B Hamilton AU - Zichen Liu AU - Darrah McCracken AU - Molly R Nixon AU - Dillon O Sylte AU - Nicholas L S Roberts AU - Oladimeji M Adebayo AU - Teamur Aghamolaei AU - Suliman A Alghnam AU - Syed Mohamed Aljunid AU - Amir Almasi-Hashiani AU - Alaa Badawi AU - Masoud Behzadifar AU - Meysam Behzadifar AU - Eyasu Tamru Bekru AU - Derrick A Bennett AU - Jens Robert Chapman AU - Kebede Deribe AU - Bereket Duko Adema AU - Yousef Fatahi AU - Belayneh K Gelaw AU - Eskezyiaw Agedew Getahun AU - Delia Hendrie AU - Andualem Henok AU - Hagos de Hidru AU - Mehdi Hosseinzadeh AU - Guoqing Hu AU - Mohammad Ali Jahani AU - Mihajlo Jakovljevic AU - Farzad Jalilian AU - Nitin Joseph AU - Manoochehr Karami AU - Abraham Getachew Kelbore AU - Md Nuruzzaman Khan AU - Yun Jin Kim AU - Parvaiz A Koul AU - Carlo La Vecchia AU - Shai Linn AU - Reza Majdzadeh AU - Man Mohan Mehndiratta AU - Peter T N Memiah AU - Melkamu Merid Mengesha AU - Hayimro Edemealem Merie AU - Ted R Miller AU - Mehdi Mirzaei-Alavijeh AU - Aso Mohammad Darwesh AU - Naser Mohammad Gholi Mezerji AU - Roghayeh Mohammadibakhsh AU - Yoshan Moodley AU - Maziar Moradi-Lakeh AU - Kamarul Imran Musa AU - Bruno Ramos Nascimento AU - Rajan Nikbakhsh AU - Peter S Nyasulu AU - Ahmed Omar Bali AU - Obinna E Onwujekwe AU - Sanghamitra Pati AU - Reza Pourmirza Kalhori AU - Farkhonde Salehi AU - Saeed Shahabi AU - Seifadin Ahmed Shallo AU - Morteza Shamsizadeh AU - Zeinab Sharafi AU - Sharvari Rahul Shukla AU - Mohammad Reza Sobhiyeh AU - Joan B Soriano AU - Bryan L Sykes AU - Rafael Tabarés-Seisdedos AU - Degena Bahray Bahrey Tadesse AU - Yonatal Mesfin Tefera AU - Arash Tehrani-Banihashemi AU - Boikhutso Tlou AU - Roman Topor-Madry AU - Taweewat Wiangkham AU - Mehdi Yaseri AU - Sanni Yaya AU - Muluken Azage Yenesew AU - Mustafa Z Younis AU - Arash Ziapour AU - Sanjay Zodpey AU - David M Pigott AU - Robert C Reiner, Jr AU - Simon I Hay AU - Alan D Lopez AU - Ali H Mokdad TI - Morbidity and mortality from road injuries: results from the Global Burden of Disease Study 2017 AID - 10.1136/injuryprev-2019-043302 DP - 2020 Oct 01 TA - Injury Prevention PG - i46--i56 VI - 26 IP - Suppl 2 4099 - http://injuryprevention.bmj.com/content/26/Suppl_2/i46.short 4100 - http://injuryprevention.bmj.com/content/26/Suppl_2/i46.full SO - Inj Prev2020 Oct 01; 26 AB - Background The global burden of road injuries is known to follow complex geographical, temporal and demographic patterns. While health loss from road injuries is a major topic of global importance, there has been no recent comprehensive assessment that includes estimates for every age group, sex and country over recent years.Methods We used results from the Global Burden of Disease (GBD) 2017 study to report incidence, prevalence, years lived with disability, deaths, years of life lost and disability-adjusted life years for all locations in the GBD 2017 hierarchy from 1990 to 2017 for road injuries. Second, we measured mortality-to-incidence ratios by location. Third, we assessed the distribution of the natures of injury (eg, traumatic brain injury) that result from each road injury.Results Globally, 1 243 068 (95% uncertainty interval 1 191 889 to 1 276 940) people died from road injuries in 2017 out of 54 192 330 (47 381 583 to 61 645 891) new cases of road injuries. Age-standardised incidence rates of road injuries increased between 1990 and 2017, while mortality rates decreased. Regionally, age-standardised mortality rates decreased in all but two regions, South Asia and Southern Latin America, where rates did not change significantly. Nine of 21 GBD regions experienced significant increases in age-standardised incidence rates, while 10 experienced significant decreases and two experienced no significant change.Conclusions While road injury mortality has improved in recent decades, there are worsening rates of incidence and significant geographical heterogeneity. These findings indicate that more research is needed to better understand how road injuries can be prevented.