RT Journal Article SR Electronic T1 4A.003 Post-career transition experiences of professional American football players retiring from brain-health concerns JF Injury Prevention JO Inj Prev FD BMJ Publishing Group Ltd SP A32 OP A33 DO 10.1136/injuryprev-2021-safety.99 VO 27 IS Suppl 2 A1 Kerr, Zachary A1 Walton, Samuel A1 Brett, Benjamin A1 DeFreese, JD A1 Weight, Erianne A1 Chandran, Avinash A1 Echemendia, Ruben A1 McCrea, Michael A1 Meehan, William A1 Guskiewicz, Kevin YR 2021 UL http://injuryprevention.bmj.com/content/27/Suppl_2/A32.3.abstract AB Background The long-term effects of concussions have led to concerns regarding former professional American football players’ post-career transitions. This cross-sectional study examines post-career transition experiences of former players retiring due to brain-health concerns.Methods Former players (n=1,784), recruited via National Football League (NFL) and Players’ Association contact lists, completed an online/paper questionnaire. Variables included: demographics, playing history, retirement reasons (pre-specified options), and factors helping/hindering post-career transitions (open-ended). We calculated descriptives for study variables from players reporting retirement due to brain-health concerns. Using template analysis, we coded open-ended responses to identify factors helping/hindering post-career transitions.Results Overall, 211 (11.8%) former players retired due to brain-health concerns (mean age=50.9±18.1, mean years played professionally=6.9±3.3). Alongside brain-health, other retirement reasons included: concerns about long-term physical health (n=155), mental health (n=121), and chronic pain (n=120). Factors helping post-career transitions were problem-focused (e.g., future planning, advice from older players, saving money) and emotionally-focused (e.g., faith/religion, spousal support, health provider/therapist care). Hindering factors were personal (e.g., ongoing musculoskeletal injury/pain issues, mental health concerns, poor health insurance, lacking transition plans, losing former schedule/routine), interpersonal (e.g. lacking support/empathy, being asked why they need to still work), and organizational (e.g., poor post-career transition support). These themes were also present among former players not reporting retirement due to brain-health concerns.Conclusion Numerous post-career transition issues concern former players. Multidimensional interventions that mitigate cognitive challenges, chronic pain, and occupational stressors may help optimize post-career transition coping strategies.Learning Outcomes Describe the post-career transition experiences of former players retiring from brain-health concerns.