Article Text

Download PDFPDF
Association between maternal depression and anxiety episodes and rates of childhood injuries: a cohort study from England
  1. Ruth Baker1,
  2. Denise Kendrick1,
  3. Laila J Tata2,
  4. Elizabeth Orton1
  1. 1Division of Primary Care, University of Nottingham, Nottingham, UK
  2. 2Division of Epidemiology and Public Health, University of Nottingham, Nottingham, UK
  1. Correspondence to Dr Ruth Baker, Division of Primary Care, University of Nottingham, Tower Building, University Park, Nottingham NG7 2RD, UK; ruthbaker03{at}


Background Maternal depression is common and associated with several child health outcomes. The impact on childhood injuries is underexplored, with existing studies relying on maternal reporting of injury occurrences. Using population healthcare databases from England, we assessed the association between maternal depression and/or anxiety episodes and rates of child poisonings, fractures, burns and serious injuries.

Methods We conducted a prospective cohort study of 207 048 mother-child pairs with linked primary care and hospitalisation data from the Clinical Practice Research Datalink and Hospital Episode Statistics, 1998–2013. Episodes of maternal depression and/or anxiety were identified using diagnoses, prescriptions and hospitalisations, with the child's follow-up time divided into exposed and unexposed periods. Adjusted IRRs (aIRR) for child injury during maternal mental health episodes were estimated using Poisson regression.

Results 54 702 children (26.4%) were exposed to maternal depression and/or anxiety when aged 0–4 years. During follow-up, 2614 poisonings, 6088 fractures and 4201 burns occurred. Child poisoning rates increased during episodes of maternal depression (aIRR 1.52, 95% CI 1.31 to 1.76), depression with anxiety (2.30, 1.93 to 2.75) and anxiety alone (1.63, 1.09 to 2.43). Similarly, rates of burns (1.53, 1.29 to 1.81) and fractures (1.24, 1.06 to 1.44) were greatest during depression with anxiety episodes. There was no association between maternal depression and/or anxiety and serious child injuries.

Conclusions Maternal depression and/or anxiety episodes were associated with increased rates of child poisonings, fractures and burns. While mechanisms are unclear, prompt identification and treatment of maternal depression and/or anxiety and provision of safety advice (eg, safe medication storage) may reduce child injury risk.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • Contributors All authors were involved in the conception and design of the study. RB undertook the analysis and drafted the manuscript. All authors contributed to interpreting the findings and revising the manuscript.

  • Funding This paper presents independent research funded by the National Institute for Health Research School for Primary Care Research and The University of Nottingham.

  • Disclaimer The views expressed are those of the author(s) and not necessarily those of the National Institute for Health Research, the National Health Service or the Department of Health.

  • Competing interests RB has received a PhD studentship from the National Institute for Health Research School for Primary Care Research.

  • Ethics approval This study was approved by the Independent Scientific Advisory Committee for the Medicines and Healthcare products Regulatory Agency, February 2014 (protocol 14_025R).

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement Read code lists have been included as online supplementary files.