Skip to main content
Log in

Screening for problem drinking

Comparison of CAGE and AUDIT

  • Original Articles
  • Published:
Journal of General Internal Medicine Aims and scope Submit manuscript

Abstract

OBJECTIVE: To compare self-administered versions of three questionnaires for detecting heavy and problem drinking: the CAGE, the Alcohol Use Disorders Identification Test (AUDIT), and an augmented version of the CAGE.

DESIGN: Cross-sectional surveys.

SETTING: Three Department of Veterans Affairs general medical clinics.

PATIENTS: Random sample of consenting male outpatients who consumed at least 5 drinks over the past year (“drinkers”). Heavy drinkers were oversampled.

MEASUREMENTS: An augmented version of the CAGE was included in a questionnaire mailed to all patients. The AUDIT was subsequently mailed to “drinkers.” Comparison standards, based on the tri-level World Health Organization alcohol consumption interview and the Diagnostic Interview Schedule, included heavy drinking (>14 drinks per week typically or ≥5 drinks per day at least monthly) and active DSM-IIIR alcohol abuse or dependence (positive diagnosis and at least one alcohol-related symptom in the past year). Areas under receiver operating characteristic curves (AUROCs) were used to compare screening questionnaires.

MAIN RESULTS: Of 393 eligible patients, 261 (66%) returned the AUDIT and completed interviews. For detection of active alcohol abuse or dependence, the CAGE augmented with three more questions (AUROC 0.871) performed better than either the CAGE alone or AUDIT (AUROCs 0.820 and 0.777, respectively). For identification of heavy-drinking patients, however, the AUDIT performed best (AUROC 0.870). To identify both heavy drinking and active alcohol abuse or dependence, the augmented CAGE and AUDIT both performed well, but the AUDIT was superior (AUROC 0.861).

CONCLUSIONS: For identification of patients with heavy drinking or active alcohol abuse or dependence, the self-administered AUDIT was superior to the CAGE in this population.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Buchsbaum DG, Buchanan RG, Centor RM, Schnoll SH, Lawton MJ. Screening for alcohol abuse using CAGE scores and likelihood ratios. Ann Intern Med. 1991;115:774–7.

    PubMed  CAS  Google Scholar 

  2. Connors GJ. Screening for alcohol problems. In: Allen JP, Columbus M, eds. Assessing Alcohol Problems: A Guide for Clinicians and Researchers. Bethesda, Md: National Institutes of Health; 1995;17–29. NIH publication 95–3745.

    Google Scholar 

  3. Barry KL, Fleming MF. Computerized administration of alcoholism screening tests in a primary care setting. J Am Board Fam Pract. 1990;3:93–8.

    PubMed  CAS  Google Scholar 

  4. Buchsbaum DG, Buchanan RG, Welsh J, Centor RM, Schnoll SH. Screening for drinking disorders in the elderly using the CAGE questionnaire. J Am Geriatr Soc. 1992;40:662–5.

    PubMed  CAS  Google Scholar 

  5. Chan AK, Pristach EA, Welte JW. Detection by the CAGE of alcoholism or heavy drinking in primary care outpatients and the general population. J Subst Abuse. 1994;6(2):123–35.

    Article  PubMed  CAS  Google Scholar 

  6. Chan AK, Pristach EA, Welte JW, Russell M. Use of the TWEAK test in screening for alcoholism/heavy drinking in three populations. Alcohol Clin Exp Res. 1993;17(6):1188–92.

    PubMed  CAS  Google Scholar 

  7. Cherpitel CJ. Analysis of cut points for screening instruments for alcohol problems in the emergency room. J Stud Alcohol. 1995;56:695–700.

    PubMed  CAS  Google Scholar 

  8. Cherpitel CJ, Clark WB. Ethnic differences in performance of screening instruments for identifying harmful drinking and alcohol dependence in the emergency room. Alcohol Clin Exp Res. 1995;19(3):628–34.

    Article  PubMed  CAS  Google Scholar 

  9. Jones TV, Lindsey BA, Yount P, Soltys R, Farani-Enayat B. Alcoholism screening questionnaires: are they valid in elderly medical outpatients? J Gen Intern Med. 1993;8:674–8.

    Article  PubMed  CAS  Google Scholar 

  10. Joseph CL, Ganzini L, Atkinson RM. Screening for alcohol use disorders in the nursing home. J Am Geriatr Soc. 1995;43:368–73.

    PubMed  CAS  Google Scholar 

  11. Liskow B, Campbell J, Nickel EJ, Powell BJ. Validity of the CAGE questionnaire in screening for alcohol dependence in a walk-in (triage) clinic. J Stud Alcohol. 1995;56:277–81.

    PubMed  CAS  Google Scholar 

  12. Magruder-Habib K, Stevens HA, Alling WC. Relative performance of the MAST, VAST, and CAGE versus DSM-III-R criteria for alcohol dependence. J Clin Epidemiol. 1993;46(5):435–41.

    Article  PubMed  CAS  Google Scholar 

  13. Morton J, Jones T, Manganaro M. Performance of alcoholism screening questionnaires in elderly veterans. Am J Med. 1996;101:153–9.

    Article  PubMed  CAS  Google Scholar 

  14. Bradley, KA, Donovan DM, Larson EB. How much is too much? Advising patients about safe levels of alcohol consumption. Arch Intern Med. 1993;153:2734–40.

    Article  PubMed  CAS  Google Scholar 

  15. Sanchez-Craig M, Wilkinson A, Davila R. Empirically based guidelines for moderate drinking: one year results from three studies with problem drinkers. Am J Public Health. 1995;85(6):823–8.

    PubMed  CAS  Google Scholar 

  16. Dawson DA, Grant BF, Harford TC. Variation in the association of alcohol consumption with five DSM-IV alcohol problem domains. Alcohol Clin Exp Res. 1995;19(1):66–74.

    PubMed  CAS  Google Scholar 

  17. Wechsler H, Davenport A, Dowdall G, Moeykens B, Castillo S. Health and behavioral consequences of binge drinking in college. JAMA. 1994;272:1672–7.

    Article  PubMed  CAS  Google Scholar 

  18. Fleming MF, Barry KL, Manwell LB, Johnson K, London R. Brief physician advice for problem alcohol drinkers. JAMA. 1997;277(13):1039–45.

    Article  PubMed  CAS  Google Scholar 

  19. Bien TH, Miller WR, Tonigan S. Brief interventions for alcohol problems: a review. Addiction. 1993;88:315–36.

    Article  PubMed  CAS  Google Scholar 

  20. Adams WL, Barry KL, Fleming MF. Screening for problem drinking in older primary care patients. JAMA. 1996;276:1964–7.

    Article  PubMed  CAS  Google Scholar 

  21. Saunders JB, Aasland OG, Babor TF, De La Fuente JR, Grant M. Development of the Alcohol Use Disorders Identification Test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption, II. Addiction. 1993;88:791–804.

    Article  PubMed  CAS  Google Scholar 

  22. Fleming MF, Barry KL. A three-sample test of a masked alcohol screening questionnaire. Alcohol Alcohol. 1991;26(1):81–91.

    PubMed  CAS  Google Scholar 

  23. Wallace P, Haines A. Use of a questionnaire in general practice to increase the recognition of patients with excessive alcohol consumption. BMJ. 1985;290:1949–52.

    Article  PubMed  CAS  Google Scholar 

  24. Babor TF, Grant M. From clinical research to secondary prevention—international collaboration in the development of of the Alcohol Use Disorders Identification Test (AUDIT). Alcohol Health Res World. 1989;13(4):371–4.

    Google Scholar 

  25. Saunders JB, Aasland OG, Amundsen A, Grant M. Alcohol consumption and related problems among primary health care patients: WHO collaborative project on early detection of harmful alcohol consumption, I. Addiction. 1993;88:349–62.

    Article  PubMed  CAS  Google Scholar 

  26. Saunders JB, Aasland OG. WHO Collaborative Project on Identification and Treatment of Persons with Harmful Alcohol Consumption: Report on Phase I, Development of a Screening Instrument. Geneva, Switzerland: World Health Organization, Divison of Mental Health; 1987.

    Google Scholar 

  27. Miller WR, Heather N, Hall W. Calculating standard drink units: international comparisons. Br J Addict. 1991;86:43–7.

    Article  PubMed  CAS  Google Scholar 

  28. Robins LN, Helzer JE, Croughan J, Ratcliff KS. National Institute of Mental Health Diagnostic Interview Schedule. Arch Gen Psychiatry. 1981;38:381–9.

    PubMed  CAS  Google Scholar 

  29. Fleming MF, Barry KL, MacDonald R. The Alcohol Use Disorders Identification Test (AUDIT) in a college sample. Int J Addict. 1991;26(11):1173–85.

    PubMed  CAS  Google Scholar 

  30. Schmidt A, Barry K, Fleming MF. Detection of problem drinkers: the Alcohol Use Disorders Identification Test. South Med J. 1995;88(1):52–9.

    PubMed  CAS  Google Scholar 

  31. Ingelfinger JA, Mosteller F, Thibodeau LA, Ware JH. Biostatistics in Clinical Medicine. 3rd ed. New York, NY: McGraw-Hill; 1994.

    Google Scholar 

  32. Zweig MH, Campbell G. ROC plots: a fundamental evaluation tool in clinical medicine. Clin Chem. 1993;39:561–77.

    PubMed  CAS  Google Scholar 

  33. Centor RM, Schwartz JS. An evaluation of methods for estimating the area under the ROC curve. Med Decis Making. 1985;5:149–56.

    Article  PubMed  CAS  Google Scholar 

  34. Hanley JA, McNeil BJ. A method of comparing the areas under receiver operating characteristic curves derived from the same cases. Radiology. 1983;148:839–43.

    PubMed  CAS  Google Scholar 

  35. Cutler SF, Wallace PG, Haines AP. Assessing alcohol consumption in general practice patients—a comparison between questionnaire and interview. Alcohol Alcohol. 1988;23(6):441–50.

    PubMed  CAS  Google Scholar 

  36. Isaacson HJ, Butler R, Zacharek M, Tzelepis A. Screening with the Alcohol Use Disorders Identification Test (AUDIT) in an inner city population. J Gen Intern Med. 1994;9:550–3.

    Article  PubMed  CAS  Google Scholar 

  37. Volk RJ, Steinbauer JR, Cantor SB, Holzer CE III. The Alcohol Use Disorders Identification Test (AUDIT) as a screen for at-risk patients of different racial/ethnic backgrounds. Addiction. 1997;92(2):197–206.

    Article  PubMed  CAS  Google Scholar 

  38. Harford TC. The effects of order of questions on reported alcohol consumption. Addiction. 1994;89:421–4.

    Article  PubMed  CAS  Google Scholar 

  39. Schuckit MA, Hesselbrock V, Tipp J, Anthenelli R, Bucholz K, Radziminski S. A comparison of DSM-III-R, DSM-IV and ICD-10 substance use disorders diagnoses in 1922 men and women subjects in the COGA study. Collaborative Study on the Genetics of Alcoholism. Addiction. 1994;89(12):1629–38.

    Article  PubMed  CAS  Google Scholar 

  40. Barry KL, Fleming MF. The Alcohol Use Disorders Identification Test (AUDIT) and the SMAST-13: predictive validity in a rural primary care sample. Alcohol. 1993;28(1):33–42.

    CAS  Google Scholar 

  41. Fertig JB, Allen JP, Cross GM. CAGE as a predictor of hazardous alcohol consumption in U.S. Army personnel. Alcohol Clin Exp Res. 1993;17(6):1184–7.

    PubMed  CAS  Google Scholar 

  42. Richmond R, Heather N, Wodak A, Kehoe L, Webster I. Controlled evaluation of a general practice based brief intervention for excessive drinking. Addiction. 1995;90:119–32.

    Article  PubMed  CAS  Google Scholar 

  43. CDC. Health risk factor surveys of commercial plan- and Medicaid-enrolled members of health-maintenance organizations-Michigan 1995. MMWR. 1997;46(39):923–6.

    Google Scholar 

  44. Buchsbaum DG, Buchanan RG, Poses RM, Schnoll SH, Lawton MJ. Physician detection of drinking problems in patients attending a general medicine practice. J Gen Intern Med. 1992;7(5):517–21.

    Article  PubMed  CAS  Google Scholar 

  45. Buchsbaum DG, Buchanan RG, Lawton MJ, Elswick RKJ, Schnoll SH. A program of screening and prompting improves short-term physician counseling of dependent and nondependent harmful drinkers. Arch Intern Med. 1993;153(13):1573–7.

    Article  PubMed  CAS  Google Scholar 

  46. Goldberg HI, Mullen M, Ries RK, Psaty BM, Ruch BP. Alcohol counseling in a general medicine clinic: a randomized controlled trial to improve referral and show rates. Med Care. 1991;29(7 suppl):JS49–56.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Consortia

Additional information

This research was supported by Department of Veteran Affairs, Hines Center for Cooperative Studies in Health Services Research, grant 91-007, and Health Services Research and Development, grant SDR 96-002, Ambulatory Care Quality Improvement Project (ACQUIP); a grant from the University of Washington Alcohol and Drug Abuse Institute; and the Health Services Research and Development Field Program and Medical Service, Seattle Division, VA Pudget Sound Health Care System.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bradley, K.A., Bush, K.R., McDonell, M.B. et al. Screening for problem drinking. J GEN INTERN MED 13, 379–388 (1998). https://doi.org/10.1046/j.1525-1497.1998.00118.x

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1046/j.1525-1497.1998.00118.x

Key words

Navigation