Clinical articleThe relationship of cigarette smoking to impaired intraoral wound healing: A review of evidence and implications for patient care
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Wound Repair
Cited by (148)
Prevention of Infection in Foot and Ankle Surgery
2019, Clinics in Podiatric Medicine and SurgeryCitation Excerpt :Specific to surgical outcomes, nicotine use is an independent risk factor for SSI because it delays primary wound healing. This is, in part, due to microvasculature constriction and microcirculation congestion due to platelet aggregation45 and nonfunctioning hemoglobin.46,47 Many articles have shown an increase in wound complications and infection after surgery in patients who smoke versus nonsmokers.48–51
Influence of nicotine on orthodontic tooth movement: A systematic review of experimental studies in rats
2018, Archives of Oral BiologyCitation Excerpt :Moreover, nicotine induces osteoblastic apoptosis and increases osteoclastic activity (Costa-Rodrigues, Rocha, & Fernandes, 2018; Marinucci et al., 2018). Furthermore, nicotine induces epinephrine and norepinephrine release from postganglionic sympathetic nerves, which limits tissue perfusion and induces vasoconstriction (Jones & Triplett, 1992). Macroscopically, this affects healing and tissue perfusion due to micro clot formation in the blood vessels (Ghanem et al., 2017; Mosely & Finseth, 1977; Sherwin & Gastwirth, 1990).
Stress Reduction Protocol
2018, Misch's Avoiding Complications in Oral ImplantologyA systematic review and meta-analysis of pre-clinical studies assessing the effect of nicotine on osseointegration
2017, International Journal of Oral and Maxillofacial Surgery
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Clinical Fellow in Facial Cosmetic Surgery, Stevens Memorial Hospital, Edmonds, WA.
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Professor and Chairman of Oral and Maxillofacial Surgery, Baylor College of Dentistry, Dallas, TX.