| Substance use disorders and mood and anxiety disorders | Unintentional poisoning by | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Illicit opioid | Prescription opioids | Non-opioid analgesics | Sedatives and hypnotics | |||||||||
| RR | 95% CI | RR | 95% CI | RR | 95% CI | RR | 95% CI | |||||
| Female | ||||||||||||
| Alcohol dependence | 1.07 | n.s. | 0.96 to 1.20 | 0.93 | n.s. | 0.86 to 1.01 | 1.29 | *** | 1.18 to 1.40 | 0.79 | ** | 0.68 to 0.93 |
| Drug dependence | 1.92 | *** | 1.81 to 2.05 | 1.50 | *** | 1.44 to 1.56 | 1.26 | *** | 1.18 to 1.36 | 1.60 | *** | 1.48 to 1.74 |
| Tobacco use disorder | 1.41 | *** | 1.34 to 1.49 | 1.22 | *** | 1.18 to 1.26 | 1.19 | *** | 1.14 to 1.25 | 1.09 | ** | 1.03 to 1.16 |
| Bipolar disorder | 1.00 | n.s. | 0.93 to 1.08 | 1.05 | * | 1.01 to 1.10 | 1.01 | n.s. | 0.95 to 1.08 | 1.19 | *** | 1.10 to 1.29 |
| Depressive disorder | 1.06 | * | 1.00 to 1.12 | 1.12 | *** | 1.08 to 1.15 | 1.18 | *** | 1.13 to 1.23 | 1.43 | *** | 1.36 to 1.51 |
| Anxiety disorder | 0.96 | n.s. | 0.90 to 1.03 | 1.01 | n.s. | 0.97 to 1.06 | 0.99 | n.s. | 0.94 to 1.05 | 1.02 | n.s. | 0.95 to 1.09 |
| Alcohol poisoning | 1.15 | n.s. | 0.98 to 1.35 | 1.08 | n.s. | 0.96 to 1.21 | 1.00 | n.s. | 0.86 to 1.16 | 1.13 | n.s. | 0.94 to 1.37 |
| Multidrug poisoning | 1.81 | *** | 1.72 to 1.90 | 1.40 | *** | 1.35 to 1.44 | 1.36 | *** | 1.30 to 1.41 | 1.58 | *** | 1.50 to 1.66 |
| Tranquilisers | Antidepressants | Other psychotropic agents | Nervous system | |||||||||
| RR | 95% CI | RR | 95% CI | RR | 95% CI | RR | 95% CI | |||||
| Alcohol dependence | 1.14 | *** | 1.06 to 1.22 | 1.31 | *** | 1.14 to 1.52 | 0.95 | n.s. | 0.85 to 1.06 | 1.00 | n.s. | 0.87 to 1.15 |
| Drug dependence | 1.26 | *** | 1.20 to 1.32 | 1.20 | ** | 1.06 to 1.36 | 1.47 | *** | 1.38 to 1.56 | 1.33 | *** | 1.21 to 1.45 |
| Tobacco use disorder | 1.17 | *** | 1.12 to 1.21 | 1.16 | *** | 1.07 to 1.25 | 1.39 | *** | 1.32 to 1.46 | 1.28 | *** | 1.20 to 1.35 |
| Bipolar disorder | 1.51 | *** | 1.45 to 1.58 | 2.03 | *** | 1.84 to 2.24 | 1.29 | *** | 1.22 to 1.37 | 1.27 | *** | 1.18 to 1.37 |
| Depressive disorder | 1.40 | *** | 1.35 to 1.45 | 2.18 | *** | 2.02 to 2.36 | 0.94 | * | 0.88 to 0.99 | 1.09 | ** | 1.02 to 1.16 |
| Anxiety disorder | 1.24 | *** | 1.19 to 1.29 | 1.09 | n.s. | 0.99 to 1.19 | 0.92 | * | 0.85 to 0.99 | 0.99 | n.s. | 0.92 to 1.07 |
| Alcohol poisoning | 1.36 | *** | 1.26 to 1.48 | 1.49 | *** | 1.23 to 1.79 | 1.34 | *** | 1.17 to 1.53 | 0.82 | n.s. | 0.66 to 1.02 |
| Multidrug poisoning | 2.11 | *** | 2.04 to 2.18 | 3.02 | *** | 2.82 to 3.24 | 1.48 | *** | 1.41 to 1.55 | 2.03 | *** | 1.93 to 2.13 |
†Estimated from Poisson regression adjusting for patient's age, race, primary payer, census region, location of residence and median income of patient's ZIP Code.
***p<0.001; **p<0.01; *p<0.05.