Table 3

Examples of study designs commonly used in the evaluation of injury interventions: quasiexperimental designs

Adapted from Shortell and Richardson, 1978.23
(1) Single time series design
Group 1Multiple observations→intervene→multiple observations
    Examples: monitored national trend in poisonings before and after child resistant packaging required for oral prescription drugs46; monitored trend in homicides in Washington, DC, before and after gun control law enacted47
(2) Multiple time series design
Group 1Multiple observations→intervene→multiple observations
Group 2Multiple observations→no action→multiple observations
    Examples: monitored trends in fire related injury rates in intervention and comparison areas before and after smoke detector giveaway program in Oklahoma City16; monitored trends in alcohol related fatal crashes in intervention and comparison areas before and after community intervention in Massachusetts29
(3) Non-equivalent control group design
Group 1Observe→intervene→observe
Group 2Observe→no action→observe
    Examples: assessed bicycle helmet use in intervention and comparison areas before and after helmet law went into effect in Maryland7; assessed child restraint use in Tennessee and Kentucky in intervention and comparison areas before and after child restraint law went into effect in Tennessee48; assessed motor vehicle crashes involving teenaged drivers in intervention and comparison areas in Connecticut before and after funding for driver education eliminated49
(4) Sequential cohort designs
Group 1Intervene→observe
Group 2No action→observe
    Example: assessed child poisonings after mothers of one birth cohort in New Zealand received poison prevention instructions and Mr Yuk labels while mothers of next birth cohort received neither50
Group 1Observe→intervene→observe→no action→observe
Group 2Observe→no action→observe→intervene→observe
    Example: assessed before and after knowledge and attitudes of sequential cohorts of children attending a safety village in Maryland19
(5) Case-control design
Group 1Select persons with injury of interest
Group 2Select matched control group without that injury
Then observe retrospectively presence or absence of intervention in the two groups
    Example: presence or absence of bicycle helmet use recorded in persons treated in Seattle emergency departments for head or non-head bicycle related injuries51