Article Text
Cochrane corner
Thousands of lives could be saved using tranexamic acid for patients with bleeding trauma
Statistics from Altmetric.com
- Antifibrinolytic agents
- tranexamic acid
- blood loss
- wounds and injuries
- haemorrhage
- concussion
- behaviour change
- public health
- pedestrian
- implementation / translation
- penetrating injury
- spinal cord injury
- traumatic brain injury
- health education
- helmet
A systematic review of randomised controlled trials of the effectiveness of tranexamic acid (TXA), which reduces clot breakdown, in patients with bleeding after severe injury shows that this inexpensive drug could save tens of thousands of lives a year.1 The review found that TXA reduces the risk of death in injured patients with severe bleeding by about 10% compared with giving no treatment. This would equate to more than 70 000 …